Article
The Association of PNPLA3, COX-2 and DHCR7 Polymorphisms with Advanced Liver Fibrosis in Patients with HCV Mono- Infection and HCV/HIV Co-Infection
Asian Pacific journal of cancer prevention : APJCP - 24 Aug 2018
Kiatbumrung Rattanaporn, Chuaypen Natthaya, Payungporn Sunchai, Avihingsanon Anchalee, Tangkijvanich Pisit
Abstract excerpt
There is increasing evidence that host genetic variations may influence the natural history of chronic hepatitis C virus (HCV) infection. The aim of this study was to determine the association between single nucleotide polymorphisms (SNPs) of PNPLA3 (rs738409), COX-2 (rs689465) and DHCR7 (rs12785878) and advanced liver fibrosis in Thai patients. A total of 220 patients with HCV mono-infection, 200 patients with...
Read the complete abstract on PubMed