PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: A repeated measures study.

doi:10.1016/j.jcv.2018.04.008

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Article

PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: A repeated measures study.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2018

Jiménez-Sousa María Ángeles, Gómez-Moreno Ana Zaida, Pineda-Tenor Daniel, Sánchez-Ruano Juan José, Fernández-Rodríguez Amanda, Artaza-Varasa Tomas, Gómez-Sanz Alicia, Martín-Vicente María, Vázquez-Morón Sonia, Resino Salvador

Abstract excerpt

BACKGROUND: Host genetic background has been associated with liver fibrosis progression. OBJECTIVE: To analyze the association between the patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 polymorphism and liver fibrosis progression in hepatitis C virus (HCV)-infected patients. STUDY DESIGN: In this retrospective cohort study, 187 patients with chronic HCV infection were included, who had at least...

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PMID: 29674183
DOI: 10.1016/j.jcv.2018.04.008

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PNPLA3

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