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Article

Single molecule based SNP detection using designed DNA carriers and solid-state nanopores.

Chemical communications (Cambridge, England) - 22 Dec 2016

Kong Jinglin, Zhu Jinbo, Keyser Ulrich F

Abstract excerpt

Single nucleotide polymorphisms (SNPs) play a crucial role as molecular markers in medical and diagnostic application. We demonstrate a nanopore based method for SNP detection at the single molecule level. Designed DNA carriers are used to distinguish DNA strands containing only one single base difference and follow strand displacement kinetics.

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PMID: 27965988
DOI: 10.1039/c6cc08621g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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