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Aurora Kinase Inhibitors - Rising Stars in Cancer Therapeutics?

1 Feb 2010

Abstract excerpt

Standard therapeutic approaches of cytotoxics and radiation in cancer are not only highly toxic, but also of limited efficacy in treatment of a significant number of cancer patients. The molecular analysis of the cancer genomes have shown a remarkable complexity and pointed to key genomic and epigenomic alterations in cancer. These discoveries are paving the way for targeted therapy approaches. However, although...

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PMID: 20124450
DOI: 10.1158/1535-7163.mct-09-0765

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