Understanding How Smoking Increases Cancer Risk.

Abstract excerpt

An in-depth computational analysis is helping to unravel the molecular mechanisms by which smoking increases the likelihood of cancer. The researchers uncovered several distinct smoking-related mutational signatures, including one thought to be the direct consequence of replicating carcinogen-damaged DNA, and another that may result in a normal clocklike mutational process being sped up.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA Methylation
• Share to Genetic Predisposition to Disease
• Share to Genome-Wide Association Study