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Article

Smoke-Induced Changes to the Epigenome Provide Fertile Ground for Oncogenic Mutation.

Cancer cell - 11 Sept 2017

Clark Susan J, Molloy Peter L

Abstract excerpt

How genetic and epigenetic events synergize to generate the oncogenic state is not well understood. In this issue of Cancer Cell, Vaz et al. provide compelling evidence that exposure to chronic cigarette smoke causes progressive epigenetic alterations that prime for key genetic events to drive the development of lung cancer.

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Identifiers

PMID: 28898692
DOI: 10.1016/j.ccell.2017.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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