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Decomposing the mutational landscape of cancer genomes with RepairSig.

Cell systems - 20 Oct 2021

Bernardo Sara, Meyenberg Mathilde, Loizou Joanna I

Abstract excerpt

Mutational signatures are the outcomes of mutagenic processes that occur prior to, and during, tumorigenesis as a result of DNA damage, DNA repair, and DNA replication. In this issue of Cell Systems, Wojtowicz et al. introduce a new computational model aimed at deconstructing the mutational processes that shape cancer genomes.

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PMID: 34672958
DOI: 10.1016/j.cels.2021.09.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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