Article
Predicting the recurrence of noncoding regulatory mutations in cancer.
BMC bioinformatics - 3 Dec 2016
Yang Woojin, Bang Hyoeun, Jang Kiwon, Sung Min Kyung, Choi Jung Kyoon
Abstract excerpt
BACKGROUND: One of the greatest challenges in cancer genomics is to distinguish driver mutations from passenger mutations. Whereas recurrence is a hallmark of driver mutations, it is difficult to observe recurring noncoding mutations owing to a limited amount of whole-genome sequenced samples. Hence, it is required to develop a method to predict potentially recurrent mutations. RESULTS: In this work, we developed...
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