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Article

Whole-exome sequencing of FFPE samples reveals mutations associated with Luminal A breast cancer recurrence.

BMC biotechnology - 11 Nov 2025

Lv Kezhen, Chen Yongxia, Zhou Jichun, Ji Feiyang, Hu Wenxian

Abstract excerpt

BACKGROUND: Early-stage Luminal A breast cancer generally has a favorable prognosis, yet some patients experience recurrence, presenting a challenge in understanding the underlying genetic factors. This study aimed to identify genetic mutations associated with recurrence in early-stage Luminal A breast cancer patients through whole-exome sequencing (WES). METHODS: We collected formalin-fixed paraffin-embedded...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41219734
DOI: 10.1186/s12896-025-01053-6
PMCID: PMC12607205

Genes

CPED1
G6PD
HMCN1
OR8U1
OR8U8
PCLO
ZCCHC18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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