Article

Transcription Factor-Centric Approach to Identify Non-Recurring Putative Regulatory Drivers in Cancer

2022-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Recent efforts to sequence the genomes of thousands of matched normal-tumor samples have led to the identification of millions of somatic mutations, the majority of which are non-coding. Most of these mutations are believed to be passengers, but a small number of non-coding mutations could contribute to tumor initiation or progression, e.g. by leading to dysregulation of gene expression. Efforts...

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Literature Corpus work: afdbea11-8a0e-593a-b3f0-cdddd449dadb
DOI: 10.1101/2022.01.31.478493

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