Shared effects of the clusterin gene on the default mode network among individuals at risk for Alzheimer's disease.

doi:10.1111/cns.12682

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Article

Shared effects of the clusterin gene on the default mode network among individuals at risk for Alzheimer's disease.

CNS neuroscience & therapeutics - 1 May 2017

Ye Qing, Su Fan, Shu Hao, Gong Liang, Xie Chun-Ming, Zhou Hong, Zhang Zhi-Jun, Bai Feng

Abstract excerpt

AIMS: To explore the common effects of the clusterin (CLU) rs11136000 variant on the default mode network (DMN) in amnestic mild cognitive impairment (aMCI) subjects and remitted geriatric depression (RGD) subjects. METHODS: Fifty-one aMCI subjects, 38 RGD subjects, and 64 cognitively normal elderly subjects underwent resting-state fMRI scans and neuropsychological tests at both baseline and a 35-month follow-up....

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PMID: 28233427
DOI: 10.1111/cns.12682
PMCID: PMC6492680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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