Article
[Epigenetics of the sperm cell].
Gynecologie, obstetrique & fertilite - 1 Sept 2006
Rousseaux S, Faure A-K, Thévenon J, Escoffier E, Lestrat C, Govin J, Hennebicq S, Sèle B, Caron C, Khochbin S
Abstract excerpt
In addition to genetic information, the spermatozoon carries another type of information, named epigenetic, which is not associated with variations of the DNA sequence. In somatic cells, it is now generally admitted that epigenetic information is not only regulated by DNA methylation but also involves modifications of the genome structure, or epigenome. During male germ cell maturation, the epigenome is globally...
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