Article
Clear Cell Type A and B Molecular Subtypes in Metastatic Clear Cell Renal Cell Carcinoma: Tumor Heterogeneity and Aggressiveness.
European urology - 1 Jun 2017
Serie Daniel J, Joseph Richard W, Cheville John C, Ho Thai H, Parasramka Mansi, Hilton Tracy, Thompson R Houston, Leibovich Bradley C, Parker Alexander S, Eckel-Passow Jeanette E
Abstract excerpt
BACKGROUND: Intratumor molecular heterogeneity has been reported for primary clear cell renal cell carcinoma (ccRCC) tumors; however, heterogeneity in metastatic ccRCC tumors has not been explored. OBJECTIVE: To evaluate intra- and intertumor molecular heterogeneity in resected metastatic ccRCC tumors. DESIGN, SETTING, AND PARTICIPANTS: We identified 111 patients who had tissue available from their primary tumor...
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