Article

Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell Carcinoma

2016-03-25

Abstract excerpt

<h4>PURPOSE</h4> Evaluation of 12 ccRCC publicly-available ccRCC gene expression datasets showed that previously proposed discrete molecular subtypes are unstable. To reflect the continuous nature of gene expression observed, we developed a quantitative score (Continuous Linear Enhanced Assessment of Renal cell carcinoma, or CLEAR) using expression analysis founded on pathologic parameters. <h4>MATERIALS AND METH...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 71f02769-1dfb-5cc2-8ded-b492fbf4dc69
DOI: 10.1101/044891

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell CarcinomaDOI 10.1101/044891Read

Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell Carcinoma.Semantic proximity Read

Clinical value and in vitro validation of gene and molecular subtype identification in renal clear cell carcinomaSemantic proximity Read

Identification of a differentiation-related prognostic nomogram based on single-cell RNA sequencing in clear cell renal cell carcinomaSemantic proximity Read

Novel Prognosis Model for Clear-cell Renal Cell Carcinoma based on Apoptosis-related GenesSemantic proximity Read

Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival PatternsSemantic proximity Read

Identification of clear cell renal cell carcinoma subtypes by integrating radiomics and transcriptomicsSemantic proximity Read

Deciphering intratumor heterogeneity in clear cell renal cell carcinoma utilizing clinicopathologic and molecular platforms.Semantic proximity Read

The single‐cell evolution trajectory presented different hypoxia heterogeneity to reveal the carcinogenesis of genes in clear cell renal cell carcinoma: Based on multiple omics and real experimental verificationSemantic proximity Read

Deep visual multi-omics profiling reveals mechanisms that underlie cancer cell differentiation and aggressiveness in clear cell renal cell carcinomaSemantic proximity Read

A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapySemantic proximity Read

Prognostic Gene Expression-Based Signature in Clear-Cell Renal Cell CarcinomaSemantic proximity Read

Integrated genomic analysis identifies subclasses and prognosis signatures of kidney cancer.Semantic proximity Read