Article
Molecular characteristics and markers of advanced clear cell renal cell carcinoma: Pitfalls due to intratumoral heterogeneity and identification of genetic alterations associated with metastasis.
International journal of urology : official journal of the Japanese Urological Association - 1 Sept 2020
Obeng Rebecca C, Arnold Rebecca S, Ogan Kenneth, Master Viraj A, Pattaras John G, Petros John A, Osunkoya Adeboye O
Abstract excerpt
OBJECTIVES: To identify clear cell renal cell carcinoma-related gene mutations potentially associated with aggressive disease, sarcomatoid differentiation or poor prognosis. METHODS: We carried out genomic analysis of 217 tumor foci from 25 patients with conventional clear cell renal cell carcinoma (14 patients), clear cell renal cell carcinoma with sarcomatoid differentiation (six patients) and non-clear cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.