Article
Tubby domain superfamily protein is required for the formation of the 7S SNARE complex in Drosophila.
Biochemical and biophysical research communications - 22 Jan 2017
Yoon Eun Jang, Jeong Yong Taek, Lee Ji Eun, Moon Seok Jun, Kim Chul Hoon
Abstract excerpt
Tubby domain superfamily protein (TUSP) is a distant member of the Tubby-like protein (TULP) family. Although other TULPs play important roles in sensation, metabolism, and development, the molecular functions of TUSP are completely unknown. Here, we explore the function of TUSP in the Drosophila nervous system where it is expressed in all neurons. Tusp mutant flies exhibit a temperature-sensitive paralysis. This...
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