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Article

Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish.

Scientific reports - 24 Nov 2016

Frisca Frisca, Colquhoun Daniel, Goldshmit Yona, Änkö Minna-Liisa, Pébay Alice, Kaslin Jan

Abstract excerpt

Lysophosphatidic acid (LPA) is a unique bioactive lysophospholipid that induces pleiotropic effects in various cell types and organisms by acting on its specific receptors. LPA is mainly synthetised extracellularly by the ectonucleotide pyrophosphatase/phosphodiesterase 2/autotaxin (enpp2). Altered LPA signalling is associated with embryonic abnormalities, suggesting critical roles for LPA during development....

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Source

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Identifiers

PMID: 27883058
DOI: 10.1038/srep37678
PMCID: PMC5121889

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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