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Article

Regulation of midline development by antagonism of lefty and nodal signaling.

Development (Cambridge, England) - 1 Jun 1999

Bisgrove B W, Essner J J, Yost H J

Abstract excerpt

The embryonic midline is crucial for the development of embryonic pattern including bilateral symmetry and left-right asymmetry. In zebrafish, lefty1 (lft1) and lefty2 (lft2) have distinct midline expression domains along the anteroposterior axis that overlap with the expression patterns of the nodal-related genes cyclops and squint. Altered expression patterns of lft1 and lft2 in zebrafish mutants that affect...

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Identifiers

PMID: 10375514
DOI: 10.1242/dev.126.14.3253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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