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Prostaglandin signaling in ciliogenesis and development

20 Dec 2021

Abstract excerpt

Prostaglandin (PG) signaling regulates a wide variety of physiological and pathological processes, including body temperature, cardiovascular homeostasis, reproduction, and inflammation. Recent studies have revealed that PGs play pivotal roles in embryo development, ciliogenesis, and organ formation. Prostaglandin E2 (PGE2) and its receptor EP4 modulate ciliogenesis by increasing the anterograde intraflagellar...

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PMID: 34927727
DOI: 10.1002/jcp.30659

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