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Understanding laterality disorders and the left-right organizer: Insights from zebrafish

23 Dec 2022

Abstract excerpt

Vital internal organs display a left-right (LR) asymmetric arrangement that is established during embryonic development. Disruption of this LR asymmetry—or laterality—can result in congenital organ malformations. Situs inversus totalis (SIT) is a complete concordant reversal of internal organs that results in a low occurrence of clinical consequences. Situs ambiguous, which gives rise to Heterotaxy syndrome...

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PMID: 36619867
DOI: 10.3389/fcell.2022.1035513

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