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Article

Prognostic value of T786C and G894T eNOS polymorphisms in sickle cell disease.

Nitric oxide : biology and chemistry - 30 Jan 2017

Armenis Iakovos, Kalotychou Vassiliki, Tzanetea Revekka, Kollia Panagoula, Kontogeorgiou Zoi, Anastasopoulou Dimitra, Mantzourani Marina, Samarkos Michael, Pantos Konstantinos, Konstantopoulos Kostas, Rombos Ioannis

Abstract excerpt

Endothelial Nitric Oxide Synthase (eNOS) is crucial for vascular homeostasis. Polymorphisms T786C and G894T affect eNOS regulation and have been related to various diseases. Sickle Cell Disease (SCD), a clinically diverse chronic hemolytic anemia, implies impaired nitric oxide bioavailability. Our aim was to determine eNOS genotype for T786C and G894T polymorphisms in Greek patients with SCD and to elucidate its...

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PMID: 27871907
DOI: 10.1016/j.niox.2016.11.002

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SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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