Article
Endothelial nitric oxide synthase gene sequence variations and vascular disease.
Molecular genetics and metabolism - 1 Aug 2000
Wang X L, Wang J
Abstract excerpt
Genes contribute significantly to interpopulation differences in vascular disease. Endothelial nitric oxide synthase (eNOS)-a key regulator of vascular nitric oxide production-has been investigated extensively to determine the relevance of DNA variants in the eNOS gene and vascular diseases. Variants in the promoter region, introns, and exons have been explored in a large number of populations but findings have...
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