Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelial nitric oxide synthase gene polymorphisms and the risk of vasculopathy in sickle cell disease.

Hematology (Amsterdam, Netherlands) - 1 Jul 2016

Yousry Sherif M, Ellithy Hend N, Shahin Gehan H

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) is one of the major health problems in many parts of the world. SCD is characterized by multisystem complications with marked variability in its severity between patients, probably linked to nitric oxide (NO). Endothelial nitric oxide synthase (eNOS) enzyme which is responsible for NO synthesis may be implicated in SCD pathophysiology. AIM OF THE STUDY: To explore the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Anemia, Sickle Cell
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to Nitric Oxide Synthase Type III

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Young Adult

Source

Identifiers

PMID: 26903375
DOI: 10.1080/10245332.2016.1142710

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelial nitric oxide synthase gene polymorphisms and the risk of vasculopathy in sickle cell disease.PMID 26903375Read ↗

Endothelial nitric oxide synthase gene intron 4 VNTR polymorphism in sickle cell disease: relation to vasculopathy and disease severity.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphism is associated with sickle cell disease patients in India.Semantic proximity Read ↗

Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphisms and Markers of Hemolysis, Inflammation and Endothelial Dysfunction in Brazilian Sickle Cell Anemia Patients.Semantic proximity Read ↗

Prognostic value of T786C and G894T eNOS polymorphisms in sickle cell disease.Semantic proximity Read ↗

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to PathophysiologySemantic proximity Read ↗

Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease.Semantic proximity Read ↗

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to Pathophysiology.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene sequence variations and vascular disease.Semantic proximity Read ↗

Pathways to pulmonary hypertension in sickle cell disease: the search for prevention and early intervention.Semantic proximity Read ↗

Mechanisms of Vasculopathy in Sickle Cell Disease and ThalassemiaSemantic proximity Read ↗

Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic PhenotypeSemantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphisms in cardiovascular disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.