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Article

T-786C variation in the promoter sequence of human eNOS gene markedly influences its expression level.

Drug discoveries & therapeutics - 1 Jan 2000

Elakkad Aliaa M, Abou-Aisha Khaled, Hassanein Sally I, Gad Mohamed Z

Abstract excerpt

This study investigated the role of the T-786C polymorphism (SNP) in the 5'-flanking sequence of the endothelial nitric oxide synthase gene (eNOS) on its expression level in vascular endothelium with the ultimate goal of shedding more light on the mechanisms by which genetic variations of eNOS might affect the vascular level of nitric oxide (NO). Sequences in the 5'-flanking region of eNOS gene were PCR-amplified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28867751
DOI: 10.5582/ddt.2016.01083

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