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Article

eNOS gene affects red cell deformability: role of T-786C, G894T, and 4a/4b polymorphisms.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Oct 2005

Fatini Cinzia, Mannini Lucia, Sticchi Elena, Cecchi Emanuele, Bruschettini Alessia, Leprini Emanuela, Pagnini Paolo, Gensini Gian Franco, Prisco Domenico, Abbate Rosanna

Abstract excerpt

Plasma viscosity and erythrocyte deformability play a key role in maintaining and regulating microcirculation. In vitro and in vivo studies suggested a role for nitric oxide (NO) in modulating flow-mediated vasodilatation and red blood cell deformability. Impaired NO availability due to mutations in eNOS gene might contribute to the altered haemorheologic state. The aim of this study was to investigate the role...

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PMID: 16244776
DOI: 10.1177/107602960501100417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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