Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity.

Emerging infectious diseases - 1 Feb 2017

Guo Hongbo, de Vries Erik, McBride Ryan, Dekkers Jojanneke, Peng Wenjie, Bouwman Kim M, Nycholat Corwin, Verheije M Helene, Paulson James C, van Kuppeveld Frank J M, de Haan Cornelis A M

Abstract excerpt

Emergence and intercontinental spread of highly pathogenic avian influenza A(H5Nx) virus clade 2.3.4.4 is unprecedented. H5N8 and H5N2 viruses have caused major economic losses in the poultry industry in Europe and North America, and lethal human infections with H5N6 virus have occurred in Asia. Knowledge of the evolution of receptor-binding specificity of these viruses, which might affect host range, is urgently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ducks
Share to Hemagglutinin Glycoproteins, Influenza Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Influenza in Birds

Share to Reassortant Viruses

Share to Receptors, Virus

Share to Viral Tropism

Share to Virus Attachment

Source

Open in PubMed Open full text

Identifiers

PMID: 27869615
DOI: 10.3201/eid2302.161072
PMCID: PMC5324792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity.PMID 27869615Read ↗

Influenza B Virus Receptor Specificity: Closing the Gap between Binding and TropismSemantic proximity Read ↗

Acquisition of human-type receptor binding specificity by new H5N1 influenza virus sublineages during their emergence in birds in Egypt.Semantic proximity Read ↗

Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research AdvancesSemantic proximity Read ↗

Sialic acid receptors: focus on their role in influenza infectionSemantic proximity Read ↗

Complex N-glycans are important for interspecies transmission of H7 influenza A viruses.Semantic proximity Read ↗

Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern ChinaSemantic proximity Read ↗

Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin.Semantic proximity Read ↗

Hemagglutinin double-mutation enhances binding of human-infecting avian influenza virus clade 2.3.4.4b H5Ny to human and SLeX receptors.Semantic proximity Read ↗

A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadthSemantic proximity Read ↗

Epistasis in the receptor binding domain of contemporary H3N2 viruses that reverted to bind sialylated diLacNAc repeatsSemantic proximity Read ↗

H7 influenza A viruses bind sialyl-LewisX, a potential intermediate receptor between speciesSemantic proximity Read ↗

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.