Article

H7 influenza A viruses bind sialyl-LewisX, a potential intermediate receptor between species

2023-12-17

Abstract excerpt

Influenza A viruses (IAVs) can overcome species barriers by adaptation of the receptor binding site of the hemagglutinin (HA). To initiate infection, HAs bind to glycan receptors with terminal sialic acids, which are either N -acetylneuraminic acid (NeuAc) or N -glycolylneuraminic acid (NeuGc), the latter is mainly found in horses and pigs but not in birds and humans. We investigated the influence of previously...

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Literature Corpus work: 932cb3d1-ff22-5a72-aed1-9222349186f1
DOI: 10.1101/2023.12.15.571923

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