Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acquisition of human-type receptor binding specificity by new H5N1 influenza virus sublineages during their emergence in birds in Egypt.

PLoS pathogens - 1 May 2011

Watanabe Yohei, Ibrahim Madiha S, Ellakany Hany F, Kawashita Norihito, Mizuike Rika, Hiramatsu Hiroaki, Sriwilaijaroen Nogluk, Takagi Tatsuya, Suzuki Yasuo, Ikuta Kazuyoshi

Abstract excerpt

Highly pathogenic avian influenza A virus subtype H5N1 is currently widespread in Asia, Europe, and Africa, with 60% mortality in humans. In particular, since 2009 Egypt has unexpectedly had the highest number of human cases of H5N1 virus infection, with more than 50% of the cases worldwide, but the basis for this high incidence has not been elucidated. A change in receptor binding affinity of the viral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ducks
Share to Hemagglutinins, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H5N1 Subtype

Share to Influenza in Birds

Share to N-Acetylneuraminic Acid

Share to Pandemics

Share to Receptors, Virus

Share to Respiratory Mucosa

Source

Open in PubMed Open full text

Identifiers

PMID: 21637809
DOI: 10.1371/journal.ppat.1002068
PMCID: PMC3102706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acquisition of human-type receptor binding specificity by new H5N1 influenza virus sublineages during their emergence in birds in Egypt.PMID 21637809Read ↗

Characterization of H5N1 influenza virus variants with hemagglutinin mutations isolated from patients.Semantic proximity Read ↗

An avian influenza H5N1 virus that binds to a human-type receptor.Semantic proximity Read ↗

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity.Semantic proximity Read ↗

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.Semantic proximity Read ↗

Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin.Semantic proximity Read ↗

Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity.Semantic proximity Read ↗

Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model FerretsSemantic proximity Read ↗

Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern ChinaSemantic proximity Read ↗

Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research AdvancesSemantic proximity Read ↗

Genetic determinants of receptor-binding preference and zoonotic potential of H9N2 avian influenza virusesSemantic proximity Read ↗

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.Semantic proximity Read ↗

Three mutations switch H7N9 influenza to human-type receptor specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.