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Article

Oncolysate-loaded Escherichia coli bacterial ghosts enhance the stimulatory capacity of human dendritic cells.

Cancer immunology, immunotherapy : CII - 1 Feb 2017

Michalek Jaroslav, Hezova Renata, Turanek-Knötigova Pavlina, Gabkova Jana, Strioga Marius, Lubitz Werner, Kudela Pavol

Abstract excerpt

The natural adjuvant properties of bacterial ghosts (BGs) lie within the presence of intact pathogen-associated molecular patterns on their surface. BGs can improve the direct delivery, natural processing and presentation of target antigens within dendritic cells (DCs). Moreover, sensitization of human DCs by cancer cell lysate (oncolysate)-loaded BGs in the presence of IFN-α and GM-CSF enhanced DC maturation as...

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Identifiers

PMID: 27864613
DOI: 10.1007/s00262-016-1932-4
PMCID: PMC11029152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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