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Lipid-polymer hybrid nanoparticles utilize B cells and dendritic cells to elicit distinct antigen-specific CD4 <sup>+</sup> and CD8 <sup>+</sup> T cell responses

2022-01-23

Abstract excerpt

Antigen presenting cells (APCs) have been extensively studied for treating cancers and autoimmune diseases. Dendritic cells (DCs) are potent APCs that uptake and present antigens (Ags) to activate immunity or tolerance. Despite their active use in cellular immunotherapies, DCs face several challenges that hinder clinical translation, such as inability to control Ag dosing for tuning immune responses and low abunda...

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Literature Corpus work
0b8bf594-eae5-5b60-9dac-173689a88e3e
DOI
10.1101/2022.01.23.477398
Open publication

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