Article
Targeting human dendritic cells in situ to improve vaccines.
Immunology letters - 1 Nov 2014
Sehgal Kartik, Dhodapkar Kavita M, Dhodapkar Madhav V
Abstract excerpt
Dendritic cells (DCs) provide a critical link between innate and adaptive immunity. The potent antigen presenting properties of DCs makes them a valuable target for the delivery of immunogenic cargo. Recent clinical studies describing in situ DC targeting with antibody-mediated targeting of DC receptor through DEC-205 provide new opportunities for the clinical application of DC-targeted vaccines. Further advances...
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