Article
T cell-specific immune response induced by bacterial ghosts.
Medical science monitor : international medical journal of experimental and clinical research - 1 Oct 2004
Felnerova Diana, Kudela Pavel, Bizik Jozef, Haslberger Alexander, Hensel Andreas, Saalmuller Armin, Lubitz Werner
Abstract excerpt
BACKGROUND: Bacterial ghosts, genetically inactivated Gram-negative bacterial pathogens, possess significant advantages over commonly used vaccination technologies. The autolysis of the bacteria, by the expression of a cloned viral gene, results in empty bacterial envelopes through the expulsion of cytoplasmic content. Immunostimulatory properties are generally presented through the targeting of professional...
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