Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

OM-197-MP-AC adjuvant properties: the in vitro maturation of normal and leukemic dendritic cells in a serum-free culture model.

Immunobiology - 1 Jan 2004

Véran Julie, Mohty Mohamad, Gaugler Béatrice, Chiavaroli Carlo, Olive Daniel

Abstract excerpt

Dendritic cells (DC) play a pivotal role in linking innate and adaptive immunity. Only mature DC are able to initiate adaptive immune responses by sensitising naive antigen-specific T cells. For clinical immunotherapeutic applications, safe and efficient clinical grade maturation factors of DC are required. Here, we investigated the impact of OM-197-MP-AC (OM-197), a synthetic lipid A analogue pseudo-dipeptide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Culture Media
Share to Culture Media, Serum-Free

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Dendritic Cells

Share to Leukemia, Myeloid

Share to Phospholipids

Share to T-Lymphocytes

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 15481142
DOI: 10.1016/j.imbio.2004.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

OM-197-MP-AC adjuvant properties: the in vitro maturation of normal and leukemic dendritic cells in a serum-free culture model.PMID 15481142Read ↗

OM197-MP-AC induces the maturation of human dendritic cells and promotes a primary T cell response.Semantic proximity Read ↗

Th1-polarizing capacity of clinical-grade dendritic cells is triggered by Ribomunyl but is compromised by PGE2: the importance of maturation cocktails.Semantic proximity Read ↗

Phenotypical and functional characterization of clinical-grade dendritic cells.Semantic proximity Read ↗

Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses.Semantic proximity Read ↗

Comparison of two different protocols for the induction of maturation of human dendritic cells in vitro.Semantic proximity Read ↗

A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines.Semantic proximity Read ↗

Interferon alpha induces generation of semi-mature dendritic cells with high pro-inflammatory and cytotoxic potential.Semantic proximity Read ↗

Dendritic cells differentiated in the presence of IFN-{beta} and IL-3 are potent inducers of an antigen-specific CD8+ T cell response.Semantic proximity Read ↗

Tumor necrosis factor-α promotes survival and phenotypic maturation of poly(I:C)-treated dendritic cells but impairs their Th1 and Th17 polarizing capability.Semantic proximity Read ↗

Different In Vitro-Generated MUTZ-3-Derived Dendritic Cell Types Secrete Dexosomes with Distinct Phenotypes and Antigen Presentation Potencies.Semantic proximity Read ↗

Comparative study of clinical grade human tolerogenic dendritic cells.Semantic proximity Read ↗

Hiltonol and Protamine-RNA stimulation induce an immune-activating transcriptome profile in cDC1sSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.