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Article

Lipopolysaccharide promotes tumorigenicity of hepatic progenitor cells by promoting proliferation and blocking normal differentiation.

Cancer letters - 1 Feb 2017

Li Xiao-Yong, Yang Xue, Zhao Qiu-Dong, Han Zhi-Peng, Liang Lei, Pan Xiao-Rong, Zhu Jing-Ni, Li Rong, Wu Meng-Chao, Wei Li-Xin

Abstract excerpt

Hepatic progenitor cells (HPCs) are bipotential stem cells that can differentiate into mature hepatocytes or biliary epithelial cells (BECs). They are thought to be involved in repair of liver injury and the incidence of hepatic carcinoma. Their physiology is closely associated with the microenvironment where they reside. Lipopolysaccharide (LPS), an important component of the hepatic pathological...

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PMID: 27864114
DOI: 10.1016/j.canlet.2016.10.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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