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Article

Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling.

Journal of cellular physiology - 1 Jan 2018

Kukolj Tamara, Trivanović Drenka, Djordjević Ivana Okić, Mojsilović Slavko, Krstić Jelena, Obradović Hristina, Janković Srdja, Santibanez Juan Francisco, Jauković Aleksandra, Bugarski Diana

Abstract excerpt

Lipopolysaccharide (LPS) is a pertinent deleterious factor in oral microenvironment for cells which are carriers of regenerative processes. The aim of this study was to investigate the emerging in vitro effects of LPS (Escherichia coli) on human periodontal ligament stem cell (PDLSC) functions and associated signaling pathways. We demonstrated that LPS did not affect immunophenotype, proliferation, viability, and...

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PMID: 28295277
DOI: 10.1002/jcp.25904

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