Article
Pooled genome wide association detects association upstream of FCRL3 with Graves' disease.
BMC genomics - 18 Nov 2016
Khong Jwu Jin, Burdon Kathryn P, Lu Yi, Laurie Kate, Leonardos Lefta, Baird Paul N, Sahebjada Srujana, Walsh John P, Gajdatsy Adam, Ebeling Peter R, Hamblin Peter Shane, Wong Rosemary, Forehan Simon P, Fourlanos Spiros, Roberts Anthony P, Doogue Matthew, Selva Dinesh, Montgomery Grant W, Macgregor Stuart, Craig Jamie E
Abstract excerpt
BACKGROUND: Graves' disease is an autoimmune thyroid disease of complex inheritance. Multiple genetic susceptibility loci are thought to be involved in Graves' disease and it is therefore likely that these can be identified by genome wide association studies. This study aimed to determine if a genome wide association study, using a pooling methodology, could detect genomic loci associated with Graves' disease....
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