Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

doi:10.1089/thy.2009.0375

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Article

Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

Thyroid : official journal of the American Thyroid Association - 1 Apr 2010

Simmonds Matthew J, Yesmin Kadija, Newby Paul R, Brand Oliver J, Franklyn Jayne A, Gough Stephen C L

Abstract excerpt

BACKGROUND: Previous genome-wide microsatellite screening in Graves' disease (GD) has suggested several regions of linkage to disease. Although replication has been inconsistent, some regions such as chromosome 5q31-33 have been associated with several Oriental GD patient cohorts. Recently, two studies have reported association of single-nucleotide polymorphism (SNP) rs31480 in interleukin 3 (IL-3) and the...

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PMID: 20210668
DOI: 10.1089/thy.2009.0375

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