Article
Sensitivity to isoflurane anesthesia increases in autism spectrum disorder Shank3+/∆c mutant mouse model.
Neurotoxicology and teratology - 1 Jan 2000
Li Changsheng, Schaefer Michele, Gray Christy, Yang Ya, Furmanski Orion, Liu Sufang, Worley Paul, Mintz C David, Tao Feng, Johns Roger A
Abstract excerpt
Autism is a heterogeneous developmental disorder characterized by impaired social interaction, impaired communication skills, and restricted and repetitive behavior. The abnormal behaviors of these patients can make their anesthetic and perioperative management difficult. Evidence in the literature suggests that some patients with autism or specific autism spectrum disorders (ASD) exhibit altered responses to...
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