Article
Behavioral profiles of mouse models for autism spectrum disorders.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2011
Ey Elodie, Leblond Claire S, Bourgeron Thomas
Abstract excerpt
Autism spectrum disorders (ASD) are characterized by impairments in reciprocal social communication, and stereotyped verbal and nonverbal behaviors. In approximately 10-25% of the affected individuals, a genetic mutation associated with the condition can be identified. Recently, mutations altering synapse formation, cellular/synaptic growth rate and regulation of excitatory and inhibitory currents were identified...
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