Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies.

CNS & neurological disorders drug targets - 1 Jan 2024

El Yacoubi Fatima Azzahrae, Oukabli Mohamed, Ibrahimi Azeddine, Kisra Hassan, Bensaid Mounia

Abstract excerpt

Autism Spectrum Disorder is a neurodevelopmental disorder characterized by impaired social and communication skills, repetitive behaviors, and/or restricted interests with a prevalence of as high as 1% of children. Autism spectrum has strongly associated with genetic factors and exhibits wide clinical and heterogeneous genetic architecture. Most genes associated with Autism are involved in neuronal and synaptic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to Cell Adhesion Molecules, Neuronal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Mutation

Share to Nerve Tissue Proteins

Source

Identifiers

PMID: 37497709
DOI: 10.2174/1871527323666230727102244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted Therapies.PMID 37497709Read ↗

Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic MechanismSemantic proximity Read ↗

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.Semantic proximity Read ↗

Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.Semantic proximity Read ↗

Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking.Semantic proximity Read ↗

A review on the current neuroligin mouse models.Semantic proximity Read ↗

Multiple rare variants in the etiology of autism spectrum disorders.Semantic proximity Read ↗

Distortion of the normal function of synaptic cell adhesion molecules by genetic variants as a risk for autism spectrum disorders.Semantic proximity Read ↗

Functions of synapse adhesion molecules neurexin/neuroligins and neurodevelopmental disorders.Semantic proximity Read ↗

Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.Semantic proximity Read ↗

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.Semantic proximity Read ↗

Neuroligin‐3‐deficient mice: model of a monogenic heritable form of autism with an olfactory deficitSemantic proximity Read ↗

Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.