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Article

Paternal Aging Affects Behavior in Pax6 Mutant Mice: A Gene/Environment Interaction in Understanding Neurodevelopmental Disorders.

PloS one - 1 Jan 2016

Yoshizaki Kaichi, Furuse Tamio, Kimura Ryuichi, Tucci Valter, Kaneda Hideki, Wakana Shigeharu, Osumi Noriko

Abstract excerpt

Neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit and hyperactivity disorder (ADHD) have increased over the last few decades. These neurodevelopmental disorders are characterized by a complex etiology, which involves multiple genes and gene-environmental interactions. Various genes that control specific properties of neural development exert pivotal roles in the occurrence...

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Identifiers

PMID: 27855195
DOI: 10.1371/journal.pone.0166665
PMCID: PMC5113965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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