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Article

Maternal separation with early weaning: a novel mouse model of early life neglect

29 Sept 2010

Abstract excerpt

BACKGROUND: Childhood adversity is associated with increased risk for mood, anxiety, impulse control, and substance disorders. Although genetic and environmental factors contribute to the development of such disorders, the neurobiological mechanisms involved are poorly understood. A reliable mouse model of early life adversity leading to lasting behavioral changes would facilitate progress in elucidating the...

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PMID: 20920223
DOI: 10.1186/1471-2202-11-123

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