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Article

Acrylamide induces specific DNA adduct formation and gene mutations in a carcinogenic target site, the mouse lung.

Mutagenesis - 1 Mar 2015

Ishii Yuji, Matsushita Kohei, Kuroda Ken, Yokoo Yuh, Kijima Aki, Takasu Shinji, Kodama Yukio, Nishikawa Akiyoshi, Umemura Takashi

Abstract excerpt

Acrylamide (AA) is a contaminant in heated foods and is carcinogenic in multiple organs of rodents. There have been many reports regarding AA-induced DNA modification and genotoxicity. However, the data are insufficient to understand fully the relationship between the two events. A recent report demonstrated carcinogenicity in the mouse lung. The lung is advantageous for investigation of AA-induced genotoxicity...

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PMID: 25392148
DOI: 10.1093/mutage/geu062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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