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Article

Time to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis.

PloS one - 1 Jan 2016

Venkatraman Lakshmi, Regan Erzsébet Ravasz, Bentley Katie

Abstract excerpt

Angiogenesis is a highly dynamic morphogenesis process; however, surprisingly little is known about the timing of the different molecular processes involved. Although the role of the VEGF-notch-DLL4 signaling pathway has been established as essential for tip/stalk cell competition during sprouting, the speed and dynamic properties of the underlying process at the individual cell level has not been fully...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Neovascularization, Physiologic

Share to Receptors, Notch

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Source

Open in PubMed Open full text

Identifiers

PMID: 27846305
DOI: 10.1371/journal.pone.0166489
PMCID: PMC5113036

Genes

DLL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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