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Article

Endothelial Tip Cells in Ocular Angiogenesis

23 Oct 2012

Abstract excerpt

Endothelial tip cells are leading cells at the tips of vascular sprouts coordinating multiple processes during angiogenesis. In the developing retina, tip cells play a tightly controlled, timely role in angiogenesis. In contrast, excessive numbers of tip cells are a characteristic of the chaotic pathological blood vessels in proliferative retinopathies. Tip cells control adjacent endothelial cells in a...

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PMID: 23092791
DOI: 10.1369/0022155412467635

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