Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of calcium oscillations in the phenotype selection in endothelial cells.

Scientific reports - 10 Dec 2021

Debir Birses, Meaney Cameron, Kohandel Mohammad, Unlu M Burcin

Abstract excerpt

Angiogenesis is an important process in the formation and maintenance of tissues which is driven by a complex system of intracellular and intercellular signaling mechanisms. Endothelial cells taking part in early angiogenesis must select their phenotype as either a tip cells (leading, migratory) or a stalk cells (following). Recent experiments have demonstrated that rapid calcium oscillations within active cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Biomarkers
Share to Calcium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium Signaling

Share to Cell Communication

Share to Cells, Cultured

Share to Endothelial Cells

Share to Models, Biological

Source

Open in PubMed Open full text

Identifiers

PMID: 34893636
DOI: 10.1038/s41598-021-02720-2
PMCID: PMC8664853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of calcium oscillations in the phenotype selection in endothelial cells.PMID 34893636Read ↗

A Computational Model of the Endothelial to Mesenchymal TransitionSemantic proximity Read ↗

Positive-feedback defines the timing and robustness of angiogenesisSemantic proximity Read ↗

Blood flow and endothelial cell phenotype regulation during sprouting angiogenesis.Semantic proximity Read ↗

Time to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis.Semantic proximity Read ↗

A review of mathematical models for the formation of vascular networksSemantic proximity Read ↗

Endothelial cell phenotypic behaviors cluster into dynamic state transition programs modulated by angiogenic and angiostatic cytokines.Semantic proximity Read ↗

Studying complex system: calcium oscillations as attractor of cell differentiation.Semantic proximity Read ↗

VEGF and Notch in tip and stalk cell selection.Semantic proximity Read ↗

Endothelial cell motility, coordination and pattern formation during vasculogenesisSemantic proximity Read ↗

A conceptual cellular interaction model of left ventricular remodelling post-MI: dynamic network with exit-entry competition strategySemantic proximity Read ↗

In vivo modulation of endothelial polarization by Apelin receptor signallingSemantic proximity Read ↗

Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells <i>in silico</i> and <i>in vivo</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.