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A Computational Model of the Endothelial to Mesenchymal Transition

12 Mar 2020

Abstract excerpt

Endothelial cells (ECs) form the lining of lymph and blood vessels. Changes in tissue requirements or wounds may cause ECs to behave as tip or stalk cells. Alternatively, they may differentiate into mesenchymal cells (MCs). These processes are known as EC activation and endothelial-to-mesenchymal transition (EndMT), respectively. EndMT, Tip, and Stalk EC behaviors all require SNAI1, SNAI2, and Matrix...

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PMID: 32226439
DOI: 10.3389/fgene.2020.00040

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