Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype.

JAMA neurology - 1 Jan 2017

Nadkarni Neelesh K, Perera Subashan, Snitz Beth E, Mathis Chester A, Price Julie, Williamson Jeff D, DeKosky Steven T, Klunk William E, Lopez Oscar L

Abstract excerpt

IMPORTANCE: Motor slowing appears in preclinical Alzheimer disease (AD), progresses with AD progression, and is associated with AD pathologic findings at autopsy. Whether amyloid-β (Aβ) is associated with gait speed in elderly individuals without dementia and whether cognition and apolipoprotein E ε4 (APOE ε4) influence this association remain unknown. OBJECTIVES: To examine the association between Aβ and gait...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid
Share to Aniline Compounds

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carbon Radioisotopes

Share to Cognition Disorders

Share to Gait Disorders, Neurologic

Share to Mental Status Schedule

Share to Positron-Emission Tomography

Share to Thiazoles

Source

Open in PubMed Open full text

Identifiers

PMID: 27842173
DOI: 10.1001/jamaneurol.2016.3474
PMCID: PMC5735996

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype.PMID 27842173Read ↗

Link among apolipoprotein E E4, gait, and cognition in neurodegenerative diseases: ONDRI study.Semantic proximity Read ↗

Elevated plasma GFAP levels in MCI link APOE ε4 allele with impaired gait speed.Semantic proximity Read ↗

Apolipoprotein E4 Allele and Gait Performance in Mild Cognitive Impairment: Results From the Gait and Brain Study.Semantic proximity Read ↗

The Relationship Between Gait Task Performance and Plasma Biomarkers for Alzheimer's Disease in Cognitively Unimpaired Older Adults and Patients with Mild Cognitive Impairment.Semantic proximity Read ↗

Associations Between Walking Pace, APOE-ε4 Genotype, and Brain Health in Middle-Aged to Older Adults.Semantic proximity Read ↗

Motor phenotype of decline in cognitive performance among community-dwellers without dementia: population-based study and meta-analysis.Semantic proximity Read ↗

Gait Variability Can Predict the Risk of Cognitive Decline in Cognitively Normal Older People.Semantic proximity Read ↗

Role of APOE genotype in gait decline and disability in aging.Semantic proximity Read ↗

Genetic risk of dementia modifies the impact of obesity on limbic white matter and spatial navigation behavior in cognitively healthy adultsSemantic proximity Read ↗

Gait phenotype from mild cognitive impairment to moderate dementia: results from the GOOD initiative.Semantic proximity Read ↗

Metabolic Syndrome Is Associated With Poor Cognition: A Population-Based Study of 70-Year-Old Adults Without Dementia.Semantic proximity Read ↗

Alzheimer's disease prevention: Apolipoprotein e4 moderates the effect of physical activity on brain beta-amyloid deposition in healthy older adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.