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Article

Role of APOE genotype in gait decline and disability in aging.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2013

Verghese Joe, Holtzer Roee, Wang Cuiling, Katz Mindy J, Barzilai Nir, Lipton Richard B

Abstract excerpt

OBJECTIVES: Although apolipoprotein E (APOE) genetic variation may influence risk of gait decline and disability in aging through multiple mechanisms, a systematic examination of this relationship has been lacking. Our objective was to quantify the risk of gait decline and disability associated with the APOE ε4 allele in aging. METHODS: We evaluated 627 community-dwelling adults aged 70 and older (white 67.8%)...

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Source

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Identifiers

PMID: 23902934
DOI: 10.1093/gerona/glt115
PMCID: PMC3805293

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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