Article
The Relationship Between Gait Task Performance and Plasma Biomarkers for Alzheimer's Disease in Cognitively Unimpaired Older Adults and Patients with Mild Cognitive Impairment.
Clinical interventions in aging - 1 Jan 2026
Sergio Jordan, Price Ashley, Snyder Peter J, Doster Savannah A, Durkin Maeve, Strenger Jennifer R, Thompson Louisa I, Stradtman Megan, Sinoff Stuart, Alber Jessica
Abstract excerpt
Purpose: The Timed Up and Go (TUG) is a 20-foot gait assessment, with TUG-dual task (DT) serial subtractions to determine dual-task cost. Alzheimer's disease (AD) risk is established using plasma biomarkers and APOE genotyping. Methods: We investigated: 1) TUG/TUG-DT differences between AD low-risk cognitively unimpaired (CU) older adults (N = 74), AD high-risk CU older adults (N = 87), and mild cognitively...
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